Lab Notes
Cold Chain: Why −20°C Actually Matters
Storage temperature is the cheapest and most-overlooked reproducibility variable.
M. Tanaka, PhD
Contributing Researcher
May 30, 2025
5 min read
Most peptide degradation in research labs starts at the freezer, not in the assay.
Freeze–thaw cycles
Aliquot before freezing. Repeated thaw cycles are one of the most consistent sources of decreased bioactivity.
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Content in the Thrive Peptides journal summarizes published research and is intended for qualified investigators. It is not medical advice and does not describe products for human consumption.
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